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{超负荷工作加速人体衰老}
《联合早报》报道 芬兰研究人员发现，严重超负荷工作会引起人体细胞基因中的染色体端粒（telomeres）缩短，加速人体衰老。
芬兰职业健康研究所的阿霍拉带领的研究小组，对2911名年龄30岁至64岁的志愿者进行了白血球细胞（leukocyte)分析；白细胞对人体免疫功能至关重要。
他们发现，面对不同工作压力的人，染色体端粒的长度有着明显的差异。工作压力大的人，端粒长度明显地比相对没有压力的人要短。
端粒在染色体的两端，作用类似于鞋带两端防止磨损的金属卡头，帮助确保染色体基因所携带的遗传指令能被准确传达，让细胞得到正确的信息。
人出生时，染色体端粒都具有一定长度，随着细胞不断分裂和老化，端粒会慢慢变短，因此端粒的长度被视为是机体生物衰老的重要指标。
当端粒达到短度的极限时，细胞就会死亡，称为凋亡过程。有些细胞不会死亡，但会出现老化，进而出现基因突变，对人体造成伤害。
研究员指出，持续超负荷工作及其引起的严重精神压力，可能导致染色体端粒缩短，引起细胞早衰，从而加速人体衰老。
慢性工作压力威胁健康
阿霍拉说：“我认为，就健康危害和改善工作条件来说，（雇主）应把此次研究结果考虑在内。慢性工作压力可能威胁健康，这是可以避免的。”
研究员建议，雇主应当跟踪调查和改善员工的工作条件，尽早发现潜在问题并及时解决，确保员工的工作量不要超负荷。
研究员指出，端粒较短也跟帕金森症、二型糖尿病、心血管病和癌症有关系。
（来源：《联合早报》）
自由空间 2012-8-13 17:19:00 | 阅读全文 | 回复(16) | 引用通告 | 编辑
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